Abcb9 Gene Summary [Rat]
Predicted to enable ABC-type transporter activity; ATP binding activity; and protein homodimerization activity. Predicted to be involved in peptide metabolic process; peptide transport; and transmembrane transport. Predicted to be located in endoplasmic reticulum membrane and lysosomal membrane. Predicted to be part of ATP-binding activity cassette (ABC) transporter complex. Predicted to be active in membrane. Orthologous to human ABCB9 (ATP binding cassette subfamily B member 9). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Abcb9 |
| Official Name | ATP binding cassette subfamily B member 9 [Source:RGD Symbol;Acc:620254] |
| Ensembl ID | ENSRNOG00000001082 |
| Bio databases IDs | |
| Aliases | ATP binding cassette subfamily B member 9 |
| Synonyms | ATP binding cassette subfamily B member 9, ATP-binding cassette, sub-family B member 9, EST122234, mKIAA1520, TAPL |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Abcb9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein
- Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein
- phosphonate ABC transporter, ATP-binding protein
- ATP binding
- Conjugate Transporter-2 (CT2) Family protein
- heme ABC exporter, ATP-binding protein CcmA
- thiol reductant ABC exporter, CydC subunit
- energy-coupling factor transporter ATPase
- nickel import ATP-binding protein NikE
- P-loop containing Nucleoside Triphosphate Hydrolases
- ATPases associated with a variety of cellular activities
- ATPase activity, coupled to transmembrane movement of substances
- SbcC/RAD50-like, Walker B motif
- peptide-transporting ATPase
- lipid A export permease/ATP-binding protein MsbA
- protein binding
- urea ABC transporter, ATP-binding protein UrtE
- ABC transporter transmembrane region
- Six-transmembrane helical domain of the ATP-binding cassette transporters
- thiol reductant ABC exporter, CydD subunit
- oligopeptide-transporting ATPase
- NHLM bacteriocin system ABC transporter, ATP-binding protein
- protein homodimerization
- ABC transporter
- ABC transporter, permease/ATP-binding protein
- transporter
Pathways
Biological processes and signaling networks where the Abcb9 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- osteoarthritis
- insomnia
- venous thromboembolism
- pervasive developmental disorder
- proliferative diabetic retinopathy
regulates
- peptide
role in cell
- autophagy in
- autophagy
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi-lysosome fractions
- membrane fraction
- intracellular membrane-bounded organelle
- cellular membrane
- lysosome
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
- lysosome membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Abcb9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- oligopeptide transmembrane transport
- transmembrane transport
- peptide metabolic process
- protein transport
- antigen processing and presentation of peptide antigen via MHC class I
- peptide transport
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- early endosome
- intracellular membrane-bounded organelle
- membrane
- endoplasmic reticulum
- lysosomal membrane
- lysosome
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- oligopeptide-transporting ATPase activity
- ATPase activity, coupled to transmembrane movement of substances
- protein homodimerization activity
- protein binding
- transmembrane transporter activity
- peptide-transporting ATPase activity