Gorab Gene Summary [Rat]
Predicted to be involved in non-motile cilium assembly. Predicted to act upstream of or within hair follicle morphogenesis and positive regulation of smoothened signaling pathway. Predicted to be located in Golgi apparatus; cytosol; and nuclear lumen. Human ortholog(s) of this gene implicated in geroderma osteodysplasticum. Orthologous to human GORAB (golgin, RAB6 interacting). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gorab |
| Official Name | golgin, RAB6-interacting [Source:RGD Symbol;Acc:1564990] |
| Ensembl ID | ENSRNOG00000003861 |
| Bio databases IDs | |
| Aliases | golgin, RAB6-interacting |
| Synonyms | GO, golgin, RAB6-interacting, NTKL-BP1, SCYL1-BP1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gorab often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- cytosol
- trans Golgi network
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Gorab gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of smoothened signaling pathway
- hair follicle morphogenesis
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- Golgi apparatus
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding