Snx13 Gene Summary [Rat]
Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in intracellular protein transport and positive regulation of GTPase activity. Predicted to be located in membrane. Predicted to be active in early endosome. Orthologous to human SNX13 (sorting nexin 13). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snx13 |
| Official Name | sorting nexin 13 [Source:RGD Symbol;Acc:1309778] |
| Ensembl ID | ENSRNOG00000004186 |
| Bio databases IDs | |
| Aliases | sorting nexin 13 |
| Synonyms | mKIAA0713, RGS-PX1, sorting nexin 13 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Snx13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Regulator of G protein signaling domain
- PXA domain
- Sorting nexin C terminal
- Regulator of G protein signaling (RGS) domain superfamily
- The Phox Homology domain, a phosphoinositide binding module
- phosphatidylinositol binding
- PX domain
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- coronary artery disease
- metabolic syndrome X
- venous thromboembolism
- primary antiphospholipid antibody syndrome
role in cell
- abnormality
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endosomes
- early endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Snx13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of signal transduction
- intracellular protein transport
- positive regulation of GTPase activity
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- early endosome
Molecular Function
What the gene product does at the molecular level
- phosphatidylinositol binding
- phosphatidylinositol-3-phosphate binding