LOC108352650 Gene Summary [Rat]
Predicted to enable zinc ion binding activity. Predicted to be a structural constituent of ribosome. Involved in positive regulation of apoptotic process. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 13. Orthologous to human RPS29 (ribosomal protein S29). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | LOC108352650 |
| Official Name | 40S ribosomal protein S29 [Source:RGD Symbol;Acc:11376557] |
| Ensembl ID | ENSRNOG00000004196 |
| Bio databases IDs | |
| Aliases | 40S ribosomal protein S29 |
| Synonyms | DBA13, FLJ11778, ribosomal protein S29, S29, uS14 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc108352650 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- Ribosomal protein S14p/S29e
- zinc ion binding
- rpsN
Pathways
Biological processes and signaling networks where the Loc108352650 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-small cell lung cancer
- biliary tract cancer
- epithelial cancer
- epithelial neoplasia
- cancer
- Diamond-Blackfan anemia type 13
- abdominal cancer
- metabolic syndrome X
- liver cancer
- liver neoplasia
regulates
- RNR
role in cell
- cell death
- apoptosis
- translation in
- processing in
- nuclear export in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Loc108352650 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- translation
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- focal adhesion
- cytoplasm
- cytosolic small ribosomal subunit
- cytosol
- small ribosomal subunit
- ribosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- structural constituent of ribosome