Eif1b Gene Summary [Rat]

Predicted to enable RNA binding activity; ribosomal small subunit binding activity; and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic 43S preinitiation complex. Orthologous to human EIF1B (eukaryotic translation initiation factor 1B). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Eif1b
Official Name
eukaryotic translation initiation factor 1B [Source:RGD Symbol;Acc:1309241]
Ensembl ID
ENSRNOG00000018848
Bio databases IDs NCBI: 301068 Ensembl: ENSRNOG00000018848
Aliases eukaryotic translation initiation factor 1B
Synonyms 1500010M16Rik, 3110001N14Rik, eukaryotic translation initiation factor 1B, GC20, RGD1309241
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Eif1b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Translation initiation factor SUI1
  • protein binding
  • translation regulator
  • Eukaryotic initiation factor 1 and related proteins

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • rheumatoid arthritis
  • peripheral arterial disease
regulated by
  • CD3 (complex)
  • NEF

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Eif1b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • translational initiation
  • regulation of translational initiation

Cellular Component

Where in the cell the gene product is active
  • eukaryotic 43S preinitiation complex

Molecular Function

What the gene product does at the molecular level
  • translation initiation factor activity
  • protein binding
  • RNA binding
  • ribosomal small subunit binding

Gene-Specific Assays for Results You Can Trust

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