Fam20b Gene Summary [Rat]

Predicted to enable phosphotransferase activity, alcohol group as acceptor. Predicted to be involved in proteoglycan biosynthetic process. Predicted to be located in cytoplasm and nucleoplasm. Predicted to colocalize with Golgi apparatus. Orthologous to human FAM20B (FAM20B glycosaminoglycan xylosylkinase). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fam20b
Official Name
FAM20B, glycosaminoglycan xylosylkinase [Source:RGD Symbol;Acc:1311162]
Ensembl ID
ENSRNOG00000004337
Bio databases IDs NCBI: 304885 Ensembl: ENSRNOG00000004337
Aliases FAM20B, glycosaminoglycan xylosylkinase
Synonyms C530043G21RIK, FAM20B glycosaminoglycan xylosylkinase, FAM20B, glycosaminoglycan xylosylkinase, gxk1, mKIAA0475, RGD1311162
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fam20b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Golgi casein kinase, C-terminal, Fam20
  • alcohol group acceptor phosphotransferase
  • FAM20_C_like
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • IL4
  • Influenza A virus (A/Japan/305/57(H2N2))
  • STAT6
regulates

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • Cytoplasm
  • Golgi Apparatus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Fam20b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteoglycan biosynthetic process
  • protein phosphorylation

Cellular Component

Where in the cell the gene product is active
  • Golgi apparatus
  • Golgi membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • protein binding
  • metal ion binding
  • phosphotransferase activity, alcohol group as acceptor
  • kinase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.