Fam20b Gene Summary [Mouse]
Predicted to enable phosphotransferase activity, alcohol group as acceptor. Predicted to be involved in proteoglycan biosynthetic process. Located in Golgi apparatus. Is expressed in articular cartilage; lower jaw; lower jaw incisor; and lower jaw molar. Orthologous to human FAM20B (FAM20B glycosaminoglycan xylosylkinase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fam20b |
| Official Name | FAM20B, glycosaminoglycan xylosylkinase [Source:MGI Symbol;Acc:MGI:2443990] |
| Ensembl ID | ENSMUSG00000033557 |
| Bio databases IDs | |
| Aliases | FAM20B, glycosaminoglycan xylosylkinase |
| Synonyms | C530043G21RIK, FAM20B glycosaminoglycan xylosylkinase, FAM20B, glycosaminoglycan xylosylkinase, gxk1, mKIAA0475, RGD1311162 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fam20b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Golgi casein kinase, C-terminal, Fam20
- alcohol group acceptor phosphotransferase
- FAM20_C_like
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Cytoplasm
- Golgi Apparatus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fam20b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteoglycan biosynthetic process
- protein phosphorylation
Cellular Component
Where in the cell the gene product is active
- Golgi apparatus
- Golgi membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- metal ion binding
- phosphotransferase activity, alcohol group as acceptor
- kinase activity