Fkbp3 Gene Summary [Rat]
Predicted to enable RNA polymerase II CTD heptapeptide repeat P3 isomerase activity and RNA polymerase II CTD heptapeptide repeat P6 isomerase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human FKBP3 (FKBP prolyl isomerase 3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fkbp3 |
| Official Name | FKBP prolyl isomerase 3 [Source:RGD Symbol;Acc:1304992] |
| Ensembl ID | ENSRNOG00000004629 |
| Bio databases IDs | |
| Aliases | FKBP prolyl isomerase 3 |
| Synonyms | FK506 binding protein 3, FKBP15, FKBP-25, FKBP prolyl isomerase 3, PPIase |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fkbp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FKBP-type peptidyl-prolyl cis-trans isomerase
- signaling receptor activity
- peptidylprolyl isomerase
- FK506 binding
- basic tilted helix bundle (BTHB) domain
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Fkbp3 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- peptidyl-prolyl cis-trans isomerase activity
- RNA binding
- protein binding
- FK506 binding
- signaling receptor activity