Hpcal1 Gene Summary [Rat]
Predicted to enable calcium ion binding activity. Predicted to be involved in regulation of signal transduction. Predicted to act upstream of or within liver development. Predicted to be located in membrane. Orthologous to human HPCAL1 (hippocalcin like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hpcal1 |
| Official Name | hippocalcin-like 1 [Source:RGD Symbol;Acc:708375] |
| Ensembl ID | ENSRNOG00000005492 |
| Bio databases IDs | |
| Aliases | hippocalcin-like 1 |
| Synonyms | BDP-1, BDR1, hippocalcin-like 1, HLP2, NVP-3, VILIP-3 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Hpcal1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EF-hand, calcium binding motif
- EF-hand domain
- EF-hand domain pair
- EF hand
- calcium ion binding
- EFh
- protein binding
- EFh_MICU
- EFh_PI-PLC
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- schizophrenia
- HER2 negative hormone receptor negative breast cancer
- peripheral arterial disease
- coronary artery disease
- dental caries
- gastric adenocarcinoma
- gastric epithelial cancer
- cytomegalovirus infection
- cerebral amyloid angiopathy
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Hpcal1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding