Cntn3 Gene Summary [Rat]
Involved in neuron projection development. Predicted to be located in plasma membrane and side of membrane. Predicted to be active in neuron projection. Orthologous to human CNTN3 (contactin 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cntn3 |
| Official Name | contactin 3 [Source:RGD Symbol;Acc:3253] |
| Ensembl ID | ENSRNOG00000006144 |
| Bio databases IDs | |
| Aliases | contactin 3 |
| Synonyms | BIG-1, contactin 3, PANG, PCS |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cntn3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- extracellular domain
- FN3
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- Fibronectin type 3 domain
- Immunoglobulin V-set domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- peripheral arterial disease
- frontal fibrosing alopecia
- renal clear cell adenocarcinoma
- renal clear cell cancer
- colon carcinoma
- colon epithelial cancer
- androgenic alopecia
role in cell
- morphology
- morphogenesis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- Extracellular Space
- photoreceptor outer segments
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cntn3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- extracellular region
- plasma membrane