Dsn1 Gene Summary [Rat]
Predicted to be involved in cell division and chromosome segregation. Predicted to act upstream of or within skeletal muscle satellite cell proliferation. Predicted to be located in cytosol; kinetochore; and nuclear lumen. Predicted to be part of MIS12/MIND type complex. Orthologous to human DSN1 (DSN1 component of MIS12 kinetochore complex). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dsn1 |
| Official Name | DSN1 component of MIS12 kinetochore complex [Source:RGD Symbol;Acc:1565179] |
| Ensembl ID | ENSRNOG00000006236 |
| Bio databases IDs | |
| Aliases | DSN1 component of MIS12 kinetochore complex |
| Synonyms | 1700022L09Rik, C20orf172, dJ469A13.2, DSN1 component of MIS12 kinetochore complex, DSN1 homolog, MIS12 kinetochore complex component, hKNL-3, KNL3, MIS13, Q9H410 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dsn1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mis12-Mtw1 protein family
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- fibrillar center
- azurophil granule lumen
- Extracellular Space
- cytosol
- nucleoplasm
- nucleoli
- nuclear bodies
- kinetochores
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Dsn1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- attachment of spindle microtubules to kinetochore
- satellite cell proliferation
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear body
- spindle pole
- cytosol
- kinetochore
- nucleolus
- extracellular region
- MIS12/MIND type complex
- azurophil granule lumen
- fibrillar center
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding