Papolg Gene Summary [Rat]

Predicted to enable metal ion binding activity and poly(A) RNA polymerase activity. Predicted to be involved in RNA 3'-end processing and mRNA processing. Predicted to be located in cytosol and nuclear body. Predicted to be active in nucleus. Orthologous to human PAPOLG (poly(A) polymerase gamma). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Papolg
Official Name
poly(A) polymerase gamma [Source:RGD Symbol;Acc:1310337]
Ensembl ID
ENSRNOG00000006261
Bio databases IDs NCBI: 305586 Ensembl: ENSRNOG00000006261
Aliases poly(A) polymerase gamma
Synonyms 9630006B20Rik, poly(A) polymerase gamma, poly(A) polymerase γ
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Papolg often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Poly(A) polymerase central domain
  • polynucleotide adenylyltransferase
  • Poly(A) polymerase predicted RNA binding domain
  • Nucleotidyltransferase (NT) domain of DNA polymerase beta and similar proteins
  • nucleotidyltransferase
  • metal ion binding
  • enzyme

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • dental caries
  • systemic lupus erythematosus
  • pelvic organ prolapse
  • dental enamel hypoplasia
  • hypodontia

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nuclear fraction
  • cytosol
  • nucleoplasm
  • nuclear bodies

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Papolg gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • RNA 3'-end processing
  • mRNA processing

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nuclear body
  • membrane
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • RNA binding
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.