Plppr1 Gene Summary [Rat]

Predicted to enable phosphatidate phosphatase activity. Involved in nervous system development. Located in neuron projection and plasma membrane. Orthologous to human PLPPR1 (phospholipid phosphatase related 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Plppr1
Official Name
phospholipid phosphatase related 1 [Source:RGD Symbol;Acc:1303116]
Ensembl ID
ENSRNOG00000007575
Bio databases IDs NCBI: 298062 Ensembl: ENSRNOG00000007575
Aliases phospholipid phosphatase related 1
Synonyms E130309F12Rik, LPPR1, mKIAA4247, phospholipid phosphatase related 1, PRG-3
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Plppr1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Acid phosphatase homologues
  • PAP2 superfamily
  • protein binding
  • PAP2_like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Parkinson disease
  • interstitial lung disease
  • vascular dementia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Plasma Membrane
  • nucleoplasm
  • neurites

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Plppr1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • phospholipid dephosphorylation
  • signal transduction
  • nervous system development
  • phospholipid metabolic process

Cellular Component

Where in the cell the gene product is active
  • neuron projection
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • phosphatidate phosphatase activity
  • lysophosphatidic acid phosphatase activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

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