Inpp5d

Enables inositol-4,5-bisphosphate 5-phosphatase activity. Predicted to be involved in several processes, including negative regulation of bone resorption; negative regulation of natural killer cell mediated cytotoxicity; and regulation of leukocyte differentiation. Predicted to act upstream of or within several processes, including determination of adult lifespan; negative regulation of B cell proliferation; and regulation of hemopoiesis. Located in actin filament and cortical cytoskeleton. Orthologous to human INPP5D (inositol polyphosphate-5-phosphatase D). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Inpp5d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Inpp5d gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Inpp5d gene, providing context for its role in the cell.