Tmcc3 Gene Summary [Rat]

Predicted to enable 14-3-3 protein binding activity and identical protein binding activity. Predicted to be located in endoplasmic reticulum. Predicted to be active in endomembrane system. Orthologous to human TMCC3 (transmembrane and coiled-coil domain family 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tmcc3
Official Name
transmembrane and coiled-coil domain family 3 [Source:RGD Symbol;Acc:1307241]
Ensembl ID
ENSRNOG00000007713
Bio databases IDs NCBI: 314751 Ensembl: ENSRNOG00000007713
Aliases transmembrane and coiled-coil domain family 3
Synonyms A230066D03Rik, AW488095, C630016B22Rik, Gm1556, Gm3588, LOC100047221, RGD1307241, Tmcc1, transmembrane and coiled-coil domain family 3, transmembrane and coiled coil domains 3
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmcc3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Predicted transmembrane and coiled-coil 2 protein
  • protein binding
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia
regulated by
role in cell
  • cell death

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • Endoplasmic Reticulum

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tmcc3 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • endomembrane system
  • endoplasmic reticulum

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding
  • 14-3-3 protein binding

Gene-Specific Assays for Results You Can Trust

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