Tmcc3 Gene Summary [Mouse]
Predicted to enable 14-3-3 protein binding activity and identical protein binding activity. Predicted to be located in endoplasmic reticulum. Predicted to be active in endomembrane system. Is expressed in several structures, including embryo mesenchyme; epithelium; forebrain; genitourinary system; and trigeminal ganglion. Orthologous to human TMCC3 (transmembrane and coiled-coil domain family 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Tmcc3 |
| Official Name | transmembrane and coiled coil domains 3 [Source:MGI Symbol;Acc:MGI:2442900] |
| Ensembl ID | ENSMUSG00000020023 |
| Bio databases IDs | |
| Aliases | transmembrane and coiled coil domains 3 |
| Synonyms | A230066D03Rik, AW488095, C630016B22Rik, Gm1556, Gm3588, LOC100047221, RGD1307241, Tmcc1, transmembrane and coiled-coil domain family 3, transmembrane and coiled coil domains 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmcc3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Predicted transmembrane and coiled-coil 2 protein
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmcc3 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- endomembrane system
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- 14-3-3 protein binding