Atg101 Gene Summary [Rat]
Predicted to enable identical protein binding activity and protein kinase binding activity. Predicted to be involved in autophagosome assembly; negative regulation of cell population proliferation; and positive regulation of autophagy. Predicted to be part of Atg1/ULK1 kinase complex. Predicted to be active in phagophore assembly site. Orthologous to human ATG101 (autophagy related 101). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Atg101 |
| Official Name | autophagy related 101 [Source:RGD Symbol;Acc:1359310] |
| Ensembl ID | ENSRNOG00000007756 |
| Bio databases IDs | |
| Aliases | autophagy related 101 |
| Synonyms | 9430023L20Rik, AA407441, AU022967, autophagy related 101, C12orf44, RGD1359310 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Atg101 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Autophagy-related protein 101
- binding protein
- protein binding
- identical protein binding
Pathways
Biological processes and signaling networks where the Atg101 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Atg101 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- autophagic vacuole assembly
- positive regulation of autophagy
- negative regulation of cell proliferation
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- pre-autophagosomal structure
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein kinase binding
- identical protein binding
- protein binding