Atg101 Gene Summary [Mouse]

Predicted to enable identical protein binding activity and protein kinase binding activity. Involved in autophagosome assembly; negative regulation of cell population proliferation; and positive regulation of autophagy. Located in phagophore assembly site. Is expressed in adrenal gland. Orthologous to human ATG101 (autophagy related 101). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Atg101
Official Name
autophagy related 101 [Source:MGI Symbol;Acc:MGI:1915368]
Ensembl ID
ENSMUSG00000037204
Bio databases IDs NCBI: 68118 Ensembl: ENSMUSG00000037204
Aliases autophagy related 101
Synonyms 9430023L20Rik, AA407441, AU022967, autophagy related 101, C12orf44, RGD1359310
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Atg101 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Autophagy-related protein 101
  • binding protein
  • protein binding
  • identical protein binding

Pathways

Biological processes and signaling networks where the Atg101 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • proliferation
  • assembly
  • autophagy by
  • cohesion in
  • cohesion

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol
  • endoplasmic reticulum membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Atg101 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • autophagic vacuole assembly
  • positive regulation of autophagy
  • negative regulation of cell proliferation

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • pre-autophagosomal structure
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein kinase binding
  • identical protein binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

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