Nap1l5 Gene Summary [Rat]

This gene encodes a protein that shares sequence similarity to nucleosome assembly factors, but may be localized to the cytoplasm rather than the nucleus. Expression of this gene is downregulated in hepatocellular carcinomas. This gene is located within a differentially methylated region (DMR) and is imprinted and paternally expressed. There is a related pseudogene on chromosome 4. [provided by RefSeq, Nov 2015]

Details

Type
Protein Coding
Official Symbol
Nap1l5
Official Name
nucleosome assembly protein 1-like 5 [Source:RGD Symbol;Acc:1584123]
Ensembl ID
ENSRNOG00000007808
Bio databases IDs NCBI: 688843 Ensembl: ENSRNOG00000007808
Aliases nucleosome assembly protein 1-like 5
Synonyms 1110020M21Rik, DRLM, LOC682844, nucleosome assembly protein 1-like 5
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nap1l5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Alzheimer disease
  • Huntington disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nap1l5 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nucleosome assembly

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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