NAP1L5 Gene Summary [Human]
This gene encodes a protein that shares sequence similarity to nucleosome assembly factors, but may be localized to the cytoplasm rather than the nucleus. Expression of this gene is downregulated in hepatocellular carcinomas. This gene is located within a differentially methylated region (DMR) and is imprinted and paternally expressed. There is a related pseudogene on chromosome 4. [provided by RefSeq, Nov 2015]
Details
| Type | Protein Coding |
| Official Symbol | NAP1L5 |
| Official Name | nucleosome assembly protein 1 like 5 [Source:HGNC Symbol;Acc:HGNC:19968] |
| Ensembl ID | ENSG00000177432 |
| Bio databases IDs | |
| Aliases | nucleosome assembly protein 1 like 5 |
| Synonyms | 1110020M21Rik, DRLM, LOC682844, nucleosome assembly protein 1-like 5 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NAP1L5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NAP1L5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nucleosome assembly
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding