Orc3

Predicted to enable DNA replication origin binding activity. Predicted to be involved in DNA replication initiation and regulation of DNA replication. Predicted to act upstream of or within glial cell proliferation and neural precursor cell proliferation. Predicted to be located in chromatin and nuclear body. Predicted to be part of DNA replication preinitiation complex; nuclear origin of replication recognition complex; and nuclear pre-replicative complex. Orthologous to human ORC3 (origin recognition complex subunit 3). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Orc3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Orc3 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Orc3 gene, providing context for its role in the cell.