Dcun1d5 Gene Summary [Rat]
Predicted to enable cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in several processes, including positive regulation of protein neddylation; protein neddylation; and regulation of cell growth. Located in nucleus. Orthologous to human DCUN1D5 (defective in cullin neddylation 1 domain containing 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dcun1d5 |
| Official Name | defective in cullin neddylation 1 domain containing 5 [Source:RGD Symbol;Acc:1307008] |
| Ensembl ID | ENSRNOG00000008390 |
| Bio databases IDs | |
| Aliases | defective in cullin neddylation 1 domain containing 5 |
| Synonyms | 3110001A18Rik, 4833420K19RIK, AW060460, D430047L21Rik, DCNL5, defective in cullin neddylation 1 domain containing 5, Hs.167721, RGD1307008, SCCRO5 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dcun1d5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PONY domain
- nuclear localization sequence
- protein binding
- Cullin binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- spindle apparatus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Dcun1d5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of cell growth
- protein neddylation
- positive regulation of protein neddylation
- response to DNA damage stimulus
- regulation of protein neddylation
Cellular Component
Where in the cell the gene product is active
- nucleus
- ubiquitin ligase complex
- cytoplasm
- spindle
Molecular Function
What the gene product does at the molecular level
- small conjugating protein binding
- ubiquitin conjugating enzyme binding
- protein binding