Cwc15 Gene Summary [Rat]

Predicted to enable RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome. Predicted to be located in mitochondrion and nuclear speck. Predicted to be part of Prp19 complex and U2-type catalytic step 2 spliceosome. Orthologous to human CWC15 (CWC15 spliceosome associated protein homolog). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cwc15
Official Name
CWC15 spliceosome-associated protein [Source:RGD Symbol;Acc:1310669]
Ensembl ID
ENSRNOG00000008490
Bio databases IDs NCBI: 300361 Ensembl: ENSRNOG00000008490
Aliases CWC15 spliceosome-associated protein
Synonyms 0610040D20Rik, 2900052N06Rik, AD002, C11orf5, CWC15 spliceosome-associated protein, CWC15 spliceosome associated protein homolog, Cwf15, Ed1, HSPC148, mED1, ORF5, RGD1310669
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cwc15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Cwf15/Cwc15 cell cycle control protein
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • disorder of pregnancy
regulated by
  • Major late
  • DAP3
  • G protein alpha
  • NOMO
role in cell
  • apoptosis
  • pluripotency
  • necroptosis
  • splicing by
  • replication in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • catalytic step 2 spliceosome
  • Mitochondria
  • spliceosomes
  • nucleoplasm
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cwc15 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nuclear mRNA cis splicing, via spliceosome
  • nuclear mRNA splicing, via spliceosome

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • catalytic step 2 spliceosome
  • nuclear speck
  • mitochondrion
  • U2-type catalytic step 2 spliceosome
  • spliceosomal complex
  • Prp19 complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.