CWC15 Gene Summary [Human]

Predicted to enable RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in mitochondrion and nuclear speck. Part of U2-type catalytic step 2 spliceosome. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
CWC15
Official Name
CWC15 spliceosome associated protein homolog [Source:HGNC Symbol;Acc:HGNC:26939]
Ensembl ID
ENSG00000150316
Bio databases IDs NCBI: 51503 Ensembl: ENSG00000150316
Aliases CWC15 spliceosome associated protein homolog
Synonyms 0610040D20Rik, 2900052N06Rik, AD002, C11orf5, CWC15 spliceosome-associated protein, CWC15 spliceosome associated protein homolog, Cwf15, Ed1, HSPC148, mED1, ORF5, RGD1310669
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CWC15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Cwf15/Cwc15 cell cycle control protein
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • disorder of pregnancy
regulated by
role in cell
  • apoptosis
  • pluripotency
  • necroptosis
  • splicing by
  • replication in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • catalytic step 2 spliceosome
  • Mitochondria
  • spliceosomes
  • nucleoplasm
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CWC15 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nuclear mRNA cis splicing, via spliceosome
  • nuclear mRNA splicing, via spliceosome

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • catalytic step 2 spliceosome
  • nuclear speck
  • mitochondrion
  • U2-type catalytic step 2 spliceosome
  • spliceosomal complex
  • Prp19 complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.