Mrpl15 Gene Summary [Rat]

Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL15 (mitochondrial ribosomal protein L15). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mrpl15
Official Name
mitochondrial ribosomal protein L15 [Source:RGD Symbol;Acc:1304796]
Ensembl ID
ENSRNOG00000008566
Bio databases IDs NCBI: 297799 Ensembl: ENSRNOG00000008566
Aliases mitochondrial ribosomal protein L15
Synonyms HSPC145, L15mt, mitochondrial ribosomal protein L15, MRP-L7, RPML7, uL15m
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mrpl15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
  • structural constituent of ribosome
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast cancer
  • chronic lymphocytic leukemia
regulated by
regulates
  • mitochondrial DNA
role in cell
  • translation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • ribosome
  • Nucleus
  • Mitochondria
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mrpl15 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

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