Krt84 Gene Summary [Rat]
Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization; keratinization; and regulation of keratinocyte differentiation. Predicted to be located in intermediate filament cytoskeleton. Predicted to be active in keratin filament. Orthologous to human KRT84 (keratin 84). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Krt84 |
| Official Name | keratin 84 [Source:RGD Symbol;Acc:1359402] |
| Ensembl ID | ENSRNOG00000008819 |
| Bio databases IDs | |
| Aliases | keratin 84 |
| Synonyms | HB4, HRb-1, Kb24, keratin 84, Krt2-16, Krt2-3, KRTHB4 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Krt84 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tropomyosin
- TPR/MLP1/MLP2-like protein
- SynN
- structural constituent of epidermis
- Intermediate filament protein
- Keratin type II head
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intermediate filament cytoskeleton
- cytosol
- keratin intermediate filaments
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Krt84 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of keratinocyte differentiation
- hair follicle development
- nail development
- keratinization
- intermediate filament organization
Cellular Component
Where in the cell the gene product is active
- keratin filament
- extracellular vesicular exosome
- cytosol
Molecular Function
What the gene product does at the molecular level
- structural constituent of epidermis
- structural constituent of cytoskeleton