Krt12

Predicted to enable structural molecule activity. Predicted to be involved in several processes, including cornea development in camera-type eye; epithelial cell differentiation; and intermediate filament organization. Predicted to act upstream of or within epithelium development. Predicted to be located in intermediate filament. Predicted to be active in cytoskeleton. Human ortholog(s) of this gene implicated in Meesmann corneal dystrophy 1 and corneal dystrophy. Orthologous to human KRT12 (keratin 12). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Krt12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Krt12 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Krt12 gene, providing context for its role in the cell.