Ddx24 Gene Summary [Rat]
Predicted to enable several functions, including ATP binding activity; RNA binding activity; and RNA helicase activity. Predicted to be active in nucleolus. Orthologous to human DDX24 (DEAD-box helicase 24). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ddx24 |
| Official Name | DEAD-box helicase 24 [Source:RGD Symbol;Acc:727929] |
| Ensembl ID | ENSRNOG00000009166 |
| Bio databases IDs | |
| Aliases | DEAD-box helicase 24 |
| Synonyms | 1700055J08Rik, 2510027P10Rik, DEAD-box helicase 24, LOC100909476 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ddx24 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- helicase superfamily c-terminal domain
- DEAD/DEAH box helicase
- N-terminal helicase domain of the DEAD-box helicase superfamily
- enzyme
- protein binding
- Helicase conserved C-terminal domain
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- neoplasia
- colon cancer
- organismal death
- metastasis
- liver cancer
- uterine leiomyoma
- leiomyomatosis
- lung cancer
- hepatocellular carcinoma
role in cell
- proliferation
- expression in
- migration
- G1/S phase transition
- senescence
- tubulation by
- acetylation in
- interaction in
- processing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ddx24 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA metabolic process
Cellular Component
Where in the cell the gene product is active
- membrane
- nucleolus
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- RNA binding
- protein binding
- RNA helicase activity