Epsti1 Gene Summary [Rat]
Predicted to act upstream of or within several processes, including cellular response to lipopolysaccharide; cellular response to type II interferon; and macrophage differentiation. Orthologous to human EPSTI1 (epithelial stromal interaction 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Epsti1 |
| Official Name | epithelial stromal interaction 1 [Source:RGD Symbol;Acc:1563207] |
| Ensembl ID | ENSRNOG00000009471 |
| Bio databases IDs | |
| Aliases | epithelial stromal interaction 1 |
| Synonyms | 2310046K10RIK, 5033415K03Rik, BRESI1, epithelial stromal interaction 1, RGD1563207 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Epsti1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- plasma cell myeloma
- neoplasia
- breast carcinoma
- HER2 negative hormone receptor negative breast cancer
- invasive breast cancer
- lung metastasis
- hyperzincemia and hypercalprotectinemia autoinflammatory syndrome
- relapsing-remitting multiple sclerosis
- irritable bowel syndrome
- ATAD3A-related type I interferonopathy
role in cell
- differentiation
- activation
- response by
- invasion by
- response
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown