Ptcd3 Gene Summary [Rat]
Predicted to enable rRNA binding activity and ribosomal small subunit binding activity. Predicted to be involved in mitochondrial translation. Predicted to be located in several cellular components, including cytosol; mitochondrial matrix; and nucleoplasm. Predicted to be part of ribonucleoprotein complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 51. Orthologous to human PTCD3 (pentatricopeptide repeat domain 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ptcd3 |
| Official Name | Pentatricopeptide repeat domain 3 [Source:RGD Symbol;Acc:1565582] |
| Ensembl ID | ENSRNOG00000009484 |
| Bio databases IDs | |
| Aliases | Pentatricopeptide repeat domain 3 |
| Synonyms | 2610034F17Rik, 2810422B04RIK, AA589622, COXPD51, MRP-S39, mS39, Pentatricopeptide repeat domain 3, TRCP2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ptcd3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- rRNA binding
- PPR repeat family
- Pentatricopeptide repeat domain
- protein binding
- ribosomal small subunit binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- Mitochondria
- cytosol
- mitochondrial matrix
- mitochondrial inner membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ptcd3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of translation
- mitochondrial translation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- cytosol
- mitochondrial small ribosomal subunit
- plasma membrane
- mitochondrial inner membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- ribosomal small subunit binding
- rRNA binding