Msl1 Gene Summary [Rat]

Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in chromatin remodeling and positive regulation of DNA-templated transcription. Predicted to be located in nuclear speck. Predicted to be part of MSL complex. Orthologous to human MSL1 (MSL complex subunit 1). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Msl1
Official Name
MSL complex subunit 1 [Source:RGD Symbol;Acc:1564778]
Ensembl ID
ENSRNOG00000009643
Bio databases IDs NCBI: 303514 Ensembl: ENSRNOG00000009643
Aliases MSL complex subunit 1
Synonyms 2810017F12Rik, 4121402D02Rik, 4930463F05Rik, male specific lethal 1, MSL complex subunit 1, RGD1564778
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Msl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PEHE domain
  • protein binding activity, bridging
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • allergic asthma
  • diabetes mellitus
regulated by
  • NUPR1
  • bone marrow-derived macrophages
regulates
role in cell
  • degradation in
  • remodeling

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Msl1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chromatin remodeling
  • positive regulation of transcription, DNA-dependent

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • MSL complex
  • nuclear speck
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • chromatin binding
  • protein binding, bridging

Gene-Specific Assays for Results You Can Trust

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