MSL1 Gene Summary [Human]
Predicted to enable chromatin binding activity. Involved in histone H4-K16 acetylation. Located in nucleoplasm. Part of MSL complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | MSL1 |
| Official Name | MSL complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:27905] |
| Ensembl ID | ENSG00000188895 |
| Bio databases IDs | |
| Aliases | MSL complex subunit 1 |
| Synonyms | 2810017F12Rik, 4121402D02Rik, 4930463F05Rik, male specific lethal 1, MSL complex subunit 1, RGD1564778 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MSL1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PEHE domain
- protein binding activity, bridging
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MSL1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chromatin remodeling
- positive regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- nucleus
- MSL complex
- nuclear speck
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- chromatin binding
- protein binding, bridging