Tas1r1 Gene Summary [Rat]

Enables taste receptor activity. Involved in sensory perception of umami taste. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human TAS1R1 (taste 1 receptor member 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tas1r1
Official Name
taste 1 receptor member 1 [Source:RGD Symbol;Acc:61891]
Ensembl ID
ENSRNOG00000009708
Bio databases IDs NCBI: 29407 Ensembl: ENSRNOG00000009708
Aliases taste 1 receptor member 1
Synonyms GM148, GPR70, T1R1, taste 1 receptor member 1, taste receptor, type 1, member 1, TR1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tas1r1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • taste receptor
  • Receptor family ligand binding region
  • Type 1 periplasmic binding fold superfamily
  • Nine Cysteines Domain of family 3 GPCR
  • 7 transmembrane sweet-taste receptor of 3 GCPR
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the Tas1r1 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • TP73
  • lactisole
  • cyclamic acid
  • L-glutamic acid
  • NOTCH
regulates
  • Ca2+
  • ERK1/2
  • VEGF
  • RPS6
  • CCK
  • L-glutamic acid
role in cell
  • phosphorylation in
  • activation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • apical compartment
  • cellular membrane
  • apical membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tas1r1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway
  • sensory perception of umami taste
  • detection of chemical stimulus involved in sensory perception of taste

Cellular Component

Where in the cell the gene product is active
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor activity
  • taste receptor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.