C2cd2l Gene Summary [Rat]
Predicted to enable insulin binding activity; phosphatidylinositol binding activity; and phosphatidylinositol transfer activity. Predicted to be involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in cortical endoplasmic reticulum; endoplasmic reticulum-plasma membrane contact site; and plasma membrane. Predicted to colocalize with cytoplasmic side of apical plasma membrane. Orthologous to human C2CD2L (C2CD2 like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | C2cd2l |
| Official Name | C2CD2-like [Source:RGD Symbol;Acc:1310281] |
| Ensembl ID | ENSRNOG00000009719 |
| Bio databases IDs | |
| Aliases | C2CD2-like |
| Synonyms | 1300006O23Rik, C2 calcium-dependent domain containing 2-like, C2CD2-like, DLNB23, LOC107984397, TMEM24 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat C2cd2l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phosphatidylinositol transporter
- protein binding
- synaptotagmin-like mitochondrial-lipid-binding protein (SMP) domain superfamily
- Synaptotagmin-like, mitochondrial and lipid-binding domain
- polypeptide hormone binding
- phosphatidylinositol binding
- transporter
- C2 domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cortical endoplasmic reticulum
- cellular membrane
- Plasma Membrane
- cytoplasmic face of plasma membrane
- synaptic vesicles
- organelle membrane contact site
- endoplasmic reticulum plasma membrane contact site
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat C2cd2l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phospholipid transport
- positive regulation of insulin secretion involved in cellular response to glucose stimulus
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- cortical endoplasmic reticulum
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- insulin binding
- protein binding
- phosphatidylinositol binding
- phosphatidylinositol transporter activity