C2cd2l Gene Summary [Mouse]

Enables insulin binding activity. Acts upstream of or within positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in membrane. Is expressed in jaw bone; nervous system; neural retina; and thoracic segment skeleton. Orthologous to human C2CD2L (C2CD2 like). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
C2cd2l
Official Name
C2 calcium-dependent domain containing 2-like [Source:MGI Symbol;Acc:MGI:1919014]
Ensembl ID
ENSMUSG00000032120
Bio databases IDs NCBI: 71764 Ensembl: ENSMUSG00000032120
Aliases C2 calcium-dependent domain containing 2-like
Synonyms 1300006O23Rik, C2 calcium-dependent domain containing 2-like, C2CD2-like, DLNB23, LOC107984397, TMEM24
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse C2cd2l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • phosphatidylinositol transporter
  • protein binding
  • synaptotagmin-like mitochondrial-lipid-binding protein (SMP) domain superfamily
  • Synaptotagmin-like, mitochondrial and lipid-binding domain
  • polypeptide hormone binding
  • phosphatidylinositol binding
  • transporter
  • C2 domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • atherosclerosis
regulated by
  • levodopa
  • F2
  • potassium chloride
  • N-methyl-D-aspartate

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cortical endoplasmic reticulum
  • cellular membrane
  • Plasma Membrane
  • cytoplasmic face of plasma membrane
  • synaptic vesicles
  • organelle membrane contact site
  • endoplasmic reticulum plasma membrane contact site

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse C2cd2l gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • phospholipid transport
  • positive regulation of insulin secretion involved in cellular response to glucose stimulus

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • cortical endoplasmic reticulum
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • insulin binding
  • protein binding
  • phosphatidylinositol binding
  • phosphatidylinositol transporter activity

Gene-Specific Assays for Results You Can Trust

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