Isy1 Gene Summary [Rat]
Enables RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleus. Part of U2-type catalytic step 1 spliceosome and catalytic step 2 spliceosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | Isy1 |
| Official Name | ISY1 splicing factor homolog [Source:RGD Symbol;Acc:1307688] |
| Ensembl ID | ENSRNOG00000010021 |
| Bio databases IDs | |
| Aliases | ISY1 splicing factor homolog |
| Synonyms | 5830446M03Rik, FSAP33, Isy1-rab43, ISY1 splicing factor homolog, KIAA1160, RGD1307688 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Isy1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Isy1-like splicing family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- catalytic step 2 spliceosome
- spliceosomes
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Isy1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- generation of catalytic spliceosome for second transesterification step
- nuclear mRNA 3'-splice site recognition
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- post-spliceosomal complex
- nucleus
- catalytic step 2 spliceosome
- post-mRNA release spliceosomal complex
- U2-type catalytic step 1 spliceosome
- Prp19 complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding