Rab30 Gene Summary [Rat]

Predicted to enable GTP binding activity and GTPase activity. Involved in Golgi organization. Located in Golgi cisterna; cis-Golgi network; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Rab30
Official Name
RAB30, member RAS oncogene family [Source:RGD Symbol;Acc:1309507]
Ensembl ID
ENSRNOG00000010224
Bio databases IDs NCBI: 308821 Ensembl: ENSRNOG00000010224
Aliases RAB30, member RAS oncogene family
Synonyms 5033421K01RIK, RAB30, member RAS oncogene family, Rsb30
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rab30 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Small GTPase of the Ras superfamily (ill-defined subfamily)
  • Ras family
  • small monomeric GTPase
  • 50S ribosome-binding GTPase
  • GTPase
  • enzyme
  • protein binding
  • Ras subfamily of RAS small GTPases
  • small GTP-binding protein domain
  • Rab subfamily of small GTPases
  • Ras of Complex, Roc, domain of DAPkinase
  • Rho (Ras homology) subfamily of Ras-like small GTPases
  • P-loop containing Nucleoside Triphosphate Hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • STAT5B
  • trans-hydroxytamoxifen
  • IFN beta
  • STAT6
  • IL4
  • eptifibatide
  • LY-411,575
  • PAGA
  • PTEN
  • collagen-related peptide
role in cell
  • proliferation
  • formation
  • organization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • intracellular nanovesicle
  • intracellular membrane-bounded organelle
  • cellular membrane
  • Plasma Membrane
  • Golgi Apparatus
  • Golgi membrane
  • Golgi stacks
  • trans Golgi network
  • cis Golgi networks
  • lysosome membrane
  • autophagic vacuoles
  • smooth endoplasmatic reticulum
  • rough endoplasmatic reticulum
  • Golgi cisternae

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Rab30 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • vesicle-mediated transport
  • Golgi organization
  • Rab protein signal transduction

Cellular Component

Where in the cell the gene product is active
  • trans-Golgi network
  • cis-Golgi network
  • intracellular membrane-bounded organelle
  • Golgi membrane
  • Golgi cisterna
  • Golgi stack

Molecular Function

What the gene product does at the molecular level
  • GTP binding
  • protein binding
  • GTPase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.