RAB30 Gene Summary [Human]
Predicted to enable GTP binding activity and GTPase activity. Involved in Golgi organization. Located in Golgi cisterna; cis-Golgi network; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RAB30 |
| Official Name | RAB30, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9770] |
| Ensembl ID | ENSG00000137502 |
| Bio databases IDs | |
| Aliases | RAB30, member RAS oncogene family |
| Synonyms | 5033421K01RIK, RAB30, member RAS oncogene family, Rsb30 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RAB30 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Small GTPase of the Ras superfamily (ill-defined subfamily)
- Ras family
- small monomeric GTPase
- 50S ribosome-binding GTPase
- GTPase
- enzyme
- protein binding
- Ras subfamily of RAS small GTPases
- small GTP-binding protein domain
- Rab subfamily of small GTPases
- Ras of Complex, Roc, domain of DAPkinase
- Rho (Ras homology) subfamily of Ras-like small GTPases
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular nanovesicle
- intracellular membrane-bounded organelle
- cellular membrane
- Plasma Membrane
- Golgi Apparatus
- Golgi membrane
- Golgi stacks
- trans Golgi network
- cis Golgi networks
- lysosome membrane
- autophagic vacuoles
- smooth endoplasmatic reticulum
- rough endoplasmatic reticulum
- Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RAB30 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- vesicle-mediated transport
- Golgi organization
- Rab protein signal transduction
Cellular Component
Where in the cell the gene product is active
- trans-Golgi network
- cis-Golgi network
- intracellular membrane-bounded organelle
- Golgi membrane
- Golgi cisterna
- Golgi stack
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding
- GTPase activity