Enpp5 Gene Summary [Rat]
Predicted to enable NAD+ diphosphatase activity and zinc ion binding activity. Involved in cell communication. Located in plasma membrane. Orthologous to human ENPP5 (ectonucleotide pyrophosphatase/phosphodiesterase family member 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Enpp5 |
| Official Name | ectonucleotide pyrophosphatase/phosphodiesterase family member 5 [Source:RGD Symbol;Acc:1359199] |
| Ensembl ID | ENSRNOG00000010232 |
| Bio databases IDs | |
| Aliases | ectonucleotide pyrophosphatase/phosphodiesterase family member 5 |
| Synonyms | AW061004, D17Abb1e, ectonucleotide pyrophosphatase/phosphodiesterase 5, ectonucleotide pyrophosphatase/phosphodiesterase family member 5, NPP-5 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Enpp5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- alkaline phosphatases and sulfatases
- Type I phosphodiesterase / nucleotide pyrophosphatase
- NAD+ diphosphatase
- zinc ion binding
- nucleotide diphosphatase
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Enpp5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell communication
Cellular Component
Where in the cell the gene product is active
- extracellular region
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- NAD+ diphosphatase activity
- zinc ion binding