Cpa4 Gene Summary [Rat]

Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in hormone catabolic process; peptide catabolic process; and proteolysis. Predicted to be active in extracellular space. Orthologous to human CPA4 (carboxypeptidase A4). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Cpa4
Official Name
carboxypeptidase A4 [Source:RGD Symbol;Acc:1563619]
Ensembl ID
ENSRNOG00000010463
Bio databases IDs NCBI: 502736 Ensembl: ENSRNOG00000010463
Aliases carboxypeptidase A4
Synonyms 1110019K20Rik, carboxypeptidase A4, CPA3, RGD1563619
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cpa4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Zinc carboxypeptidase
  • Zn_pept domain
  • peptidase
  • metallocarboxypeptidase
  • protein binding
  • M14 family of metallocarboxypeptidases and related proteins
  • Carboxypeptidase activation peptide

Pathways

Biological processes and signaling networks where the Cpa4 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • rheumatoid arthritis
  • metastatic colorectal cancer
  • diabetic nephropathy
regulated by
regulates
  • PPP2C
  • peptide
  • hormone
role in cell
  • expression in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cpa4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • peptide catabolic process
  • proteolysis
  • hormone catabolic process

Cellular Component

Where in the cell the gene product is active
  • extracellular space

Molecular Function

What the gene product does at the molecular level
  • zinc ion binding
  • metallocarboxypeptidase activity

Gene-Specific Assays for Results You Can Trust

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