Ndor1 Gene Summary [Rat]
Predicted to enable several functions, including NADPH-hemoprotein reductase activity; nucleotide binding activity; and oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor. Predicted to be involved in electron transport chain. Predicted to be located in cytoplasm; intermediate filament cytoskeleton; and nucleoplasm. Predicted to be active in cytosol. Orthologous to human NDOR1 (NADPH dependent diflavin oxidoreductase 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ndor1 |
| Official Name | NADPH dependent diflavin oxidoreductase 1 [Source:RGD Symbol;Acc:1308479] |
| Ensembl ID | ENSRNOG00000010616 |
| Bio databases IDs | |
| Aliases | NADPH dependent diflavin oxidoreductase 1 |
| Synonyms | 4930447P04Rik, AL732309.1, AL732309.2, bA350O14.9, CIAE1, LOC648245, NADPH dependent diflavin oxidoreductase 1, Ndor, NR1, Tg(UBC-cre/ERT2)1Ejb, Ubc-cre |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ndor1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FNR_like
- electron carrier
- FAD binding domain
- NADH or NADPH:heme protein oxidoreductase
- flavodoxin
- enzyme
- protein binding
- NADPH-dependent FMN reductase
- iron-sulfur protein:NAD or NADP oxidoreductase
- FAD binding
- NADPH binding
- NADP binding
- FMN binding
- sulfite reductase [NADPH] flavoprotein, alpha-component
- Oxidoreductase NAD-binding domain
- NADPH-ferrihemoprotein reductase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intermediate filament cytoskeleton
- perinuclear region
- Nucleus
- cytosol
- nucleoplasm
- cytoplasmic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ndor1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- electron transport chain
- iron-sulfur cluster assembly
Cellular Component
Where in the cell the gene product is active
- perinuclear region of cytoplasm
- intermediate filament cytoskeleton
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- FAD binding
- NADP binding
- protein binding
- FMN binding
- oxidoreductase activity
- flavin adenine dinucleotide binding
- electron carrier activity
- NADPH-hemoprotein reductase activity
- NADPH binding
- oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor
- oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor