Eral1 Gene Summary [Rat]
Predicted to enable rRNA binding activity and ribosomal small subunit binding activity. Predicted to be involved in ribosomal small subunit assembly. Predicted to be located in cytosol and mitochondrion. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in Perrault syndrome 6. Orthologous to human ERAL1 (Era like 12S mitochondrial rRNA chaperone 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Eral1 |
| Official Name | Era-like 12S mitochondrial rRNA chaperone 1 [Source:RGD Symbol;Acc:1304714] |
| Ensembl ID | ENSRNOG00000010673 |
| Bio databases IDs | |
| Aliases | Era-like 12S mitochondrial rRNA chaperone 1 |
| Synonyms | 2610524P08Rik, 9130407C09Rik, CEGA, ERA, ERAL1A, ERAL1B, Era-like 12S mitochondrial rRNA chaperone 1, ERA-W, H-ERA, HERA-A, HERA-B, M-ERA, MERA-S, MERA-W, PRLTS6 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Eral1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTP-binding protein Era
- rRNA binding
- K homology (KH) RNA-binding domain, type I
- KH domain
- 50S ribosome-binding GTPase
- hinge domain
- protein binding
- P-loop containing Nucleoside Triphosphate Hydrolases
- ribosomal small subunit binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- cytosol
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Eral1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosomal small subunit assembly
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
- cytosol
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- GTP binding
- RNA binding
- protein binding
- ribosomal small subunit binding
- rRNA binding