Coq9 Gene Summary [Rat]
Predicted to enable enzyme activator activity; isoprenoid binding activity; and protein homodimerization activity. Predicted to be involved in ubiquinone biosynthetic process. Predicted to act upstream of or within mitochondrial electron transport, NADH to ubiquinone. Predicted to be part of ubiquinone biosynthesis complex. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 5. Orthologous to human COQ9 (coenzyme Q9). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Coq9 |
| Official Name | coenzyme Q9 [Source:RGD Symbol;Acc:1586040] |
| Ensembl ID | ENSRNOG00000016190 |
| Bio databases IDs | |
| Aliases | coenzyme Q9 |
| Synonyms | 2310005O14Rik, C16orf49, coenzyme Q9, COQ10D5 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Coq9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- lipid binding
- rpsU-divergently transcribed protein
- protein homodimerization
- COQ9
- protein binding
- enzyme activator activity
- isoprenoid binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insulin resistance
- hereditary disorder
- encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
- weight loss
- demyelination
- astrocytosis
- myopathy
- primary coenzyme Q10 deficiency type 5
- paralysis
- gait disturbance
regulates
- ubiquinone
role in cell
- apoptosis
- formation
- abnormal morphology
- function
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Coq9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial electron transport, NADH to ubiquinone
- ubiquinone biosynthetic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein homodimerization activity
- protein binding
- lipid binding