Mettl15 Gene Summary [Rat]

Predicted to enable rRNA (cytosine-N4-)-methyltransferase activity. Predicted to be involved in rRNA base methylation. Predicted to be located in mitochondrial matrix. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Mettl15
Official Name
methyltransferase like 15 [Source:RGD Symbol;Acc:1304978]
Ensembl ID
ENSRNOG00000004926
Bio databases IDs NCBI: 295985 Ensembl: ENSRNOG00000004926
Aliases methyltransferase like 15
Synonyms 0610027B03Rik, methyltransferase 15, mitochondrial 12S rRNA N4-cytidine, methyltransferase like 15, METT5D1, RGD1304978
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mettl15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • rRNA (cytosine) methyltransferase
  • enzyme
  • protein binding
  • AdoMet_MTases
  • N-methyltransferase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • obesity
  • schizophrenia
  • sleep apnea syndrome
  • obstructive sleep apnea
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mettl15 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • rRNA base methylation

Cellular Component

Where in the cell the gene product is active
  • mitochondrial matrix
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • rRNA (cytosine-N4-)-methyltransferase activity

Gene-Specific Assays for Results You Can Trust

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