Acad11 Gene Summary [Rat]

Predicted to enable long-chain fatty acyl-CoA dehydrogenase activity; medium-chain fatty acyl-CoA dehydrogenase activity; and very-long-chain fatty acyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Located in peroxisome. Orthologous to human ACAD11 (acyl-CoA dehydrogenase family member 11). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Acad11
Official Name
acyl-CoA dehydrogenase family, member 11 [Source:RGD Symbol;Acc:1306270]
Ensembl ID
ENSRNOG00000010940
Bio databases IDs NCBI: 315973 Ensembl: ENSRNOG00000010940
Aliases acyl-CoA dehydrogenase family, member 11
Synonyms 5730439E10Rik, acyl-CoA dehydrogenase family member 11, acyl-CoA dehydrogenase family, member 11, acyl-Coenzyme A dehydrogenase family, member 11, RGD1306270
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Acad11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • acyl-CoA dehydrogenase
  • Protein Kinases, catalytic domain
  • Acyl-CoA dehydrogenase, C-terminal domain
  • Acyl-CoA dehydrogenase, middle domain
  • Phosphotransferase enzyme family
  • enzyme
  • protein binding
  • very-long-chain acyl-CoA dehydrogenase
  • long-chain-acyl-CoA dehydrogenase
  • Acyl-CoA dehydrogenase, N-terminal domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • COVID-19
regulated by
regulates
  • fatty acid

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • mitochondrial membrane
  • mitochondrial inner membrane
  • peroxisomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Acad11 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • fatty acid beta-oxidation using acyl-CoA dehydrogenase
  • fatty acid beta-oxidation

Cellular Component

Where in the cell the gene product is active
  • peroxisome
  • nucleus
  • mitochondrial membrane
  • cytoplasm
  • mitochondrion
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • acyl-CoA dehydrogenase activity
  • protein binding
  • medium-chain-acyl-CoA dehydrogenase activity
  • flavin adenine dinucleotide binding
  • very-long-chain-acyl-CoA dehydrogenase activity
  • long-chain-acyl-CoA dehydrogenase activity

Gene-Specific Assays for Results You Can Trust

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