ACAD11 Gene Summary [Human]
This gene encodes an acyl-CoA dehydrogenase enzyme with a preference for carbon chain lengths between 20 and 26. Naturally occurring read-through transcription occurs between the upstream gene NPHP3 (nephronophthisis 3 (adolescent)) and this gene. [provided by RefSeq, Aug 2015]
Details
| Type | Retained Intron |
| Official Symbol | ACAD11 |
| Official Name | acyl-CoA dehydrogenase family member 11 [Source:HGNC Symbol;Acc:HGNC:30211] |
| Ensembl ID | ENSG00000240303 |
| Bio databases IDs | |
| Aliases | acyl-CoA dehydrogenase family member 11 |
| Synonyms | 5730439E10Rik, acyl-CoA dehydrogenase family member 11, acyl-CoA dehydrogenase family, member 11, acyl-Coenzyme A dehydrogenase family, member 11, RGD1306270 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ACAD11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- acyl-CoA dehydrogenase
- Protein Kinases, catalytic domain
- Acyl-CoA dehydrogenase, C-terminal domain
- Acyl-CoA dehydrogenase, middle domain
- Phosphotransferase enzyme family
- enzyme
- protein binding
- very-long-chain acyl-CoA dehydrogenase
- long-chain-acyl-CoA dehydrogenase
- Acyl-CoA dehydrogenase, N-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- mitochondrial membrane
- mitochondrial inner membrane
- peroxisomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ACAD11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fatty acid beta-oxidation using acyl-CoA dehydrogenase
- fatty acid beta-oxidation
Cellular Component
Where in the cell the gene product is active
- peroxisome
- nucleus
- mitochondrial membrane
- cytoplasm
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- acyl-CoA dehydrogenase activity
- protein binding
- medium-chain-acyl-CoA dehydrogenase activity
- flavin adenine dinucleotide binding
- very-long-chain-acyl-CoA dehydrogenase activity
- long-chain-acyl-CoA dehydrogenase activity