Clmn Gene Summary [Rat]

Predicted to enable actin filament binding activity. Predicted to be involved in negative regulation of cell population proliferation and nuclear migration. Predicted to act upstream of or within neuron projection development. Predicted to be part of meiotic nuclear membrane microtubule tethering complex. Predicted to be active in cytoplasm and nuclear outer membrane. Orthologous to human CLMN (calmin). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Clmn
Official Name
calmin [Source:RGD Symbol;Acc:1306741]
Ensembl ID
ENSRNOG00000011044
Bio databases IDs NCBI: 299285 Ensembl: ENSRNOG00000011044
Aliases calmin
Synonyms 9330188N17RIK, AI788815, Calmin, KIAA0500, mKIAA1188
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Clmn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Calponin homology domain
  • calponin homology (CH) domain superfamily

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • venous thromboembolism
  • Alzheimer disease
  • colorectal adenoma
  • colorectal adenoma formation
regulated by
role in cell
  • proliferation
  • morphogenesis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Clmn gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neuron projection development
  • negative regulation of cell proliferation
  • nuclear migration

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • nuclear outer membrane
  • SUN-KASH complex

Molecular Function

What the gene product does at the molecular level
  • actin filament binding

Gene-Specific Assays for Results You Can Trust

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