Pigs Gene Summary [Rat]
Predicted to be involved in attachment of GPI anchor to protein. Predicted to be part of GPI-anchor transamidase complex. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 95. Orthologous to human PIGS (phosphatidylinositol glycan anchor biosynthesis class S). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pigs |
| Official Name | phosphatidylinositol glycan anchor biosynthesis, class S [Source:RGD Symbol;Acc:1359436] |
| Ensembl ID | ENSRNOG00000011366 |
| Bio databases IDs | |
| Aliases | phosphatidylinositol glycan anchor biosynthesis, class S |
| Synonyms | DEE95, Gm393, Gm689, GPIBD18, phosphatidylinositol glycan anchor biosynthesis class S, phosphatidylinositol glycan anchor biosynthesis, class S |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pigs often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Phosphatidylinositol-glycan biosynthesis class S protein
- enzyme
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pH resistant lipid raft fraction
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Pigs gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- attachment of GPI anchor to protein
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
- GPI-anchor transamidase complex
Molecular Function
What the gene product does at the molecular level
- protein binding