Yipf5 Gene Summary [Rat]
Predicted to be involved in Golgi vesicle transport; insulin processing; and regulation of ER to Golgi vesicle-mediated transport. Predicted to act upstream of or within Golgi organization. Predicted to be located in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum exit site. Predicted to be active in trans-Golgi network. Orthologous to human YIPF5 (Yip1 domain family member 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Yipf5 |
| Official Name | Yip1 domain family, member 5 [Source:RGD Symbol;Acc:1359165] |
| Ensembl ID | ENSRNOG00000014564 |
| Bio databases IDs | |
| Aliases | Yip1 domain family, member 5 |
| Synonyms | 2610311I19Rik, Ac2-256, FinGER5, MEDS2, SB140, SMAP-5, YIP1A, Yip1 domain family member 5, Yip1 domain family, member 5, YIPFalpha1A |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Yipf5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- N-terminal tail
- Yip1 domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- microcephaly, epilepsy, and diabetes syndrome type 2
- refractive error
regulates
- HTR1A
- insulin
- Vsvg
role in cell
- organization
- dispersal
- dispersal in
- stacking in
- stacking
- restructuring in
- restructuring
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- endomembrane system
- Golgi Apparatus
- Endoplasmic Reticulum
- granules
- nucleoplasm
- peri-Golgi vesicles
- transport vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Yipf5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ER to Golgi vesicle-mediated transport
- insulin processing
- regulation of ER to Golgi vesicle-mediated transport
- protein transport
- vesicle fusion with Golgi apparatus
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- trans-Golgi network
- intracellular membrane-bounded organelle
- Golgi apparatus
- endoplasmic reticulum
- endoplasmic reticulum exit site
- ER to Golgi transport vesicle
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding