Smap2 Gene Summary [Rat]

Predicted to enable GTPase activator activity. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human SMAP2 (small ArfGAP2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Smap2
Official Name
small ArfGAP2 [Source:RGD Symbol;Acc:1308418]
Ensembl ID
ENSRNOG00000011421
Bio databases IDs NCBI: 298500 Ensembl: ENSRNOG00000011421
Aliases small ArfGAP2
Synonyms 1810031K02Rik, LOC107984945, RGD1308418, small ArfGAP 2, SMAP1L
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Smap2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Putative GTP-ase activating proteins for the small GTPase, ARF
  • protein binding
  • GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
  • Putative GTPase activating protein for Arf

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • overall survival
  • globozoospermia
  • ulcerative colitis
regulates
role in cell
  • formation
  • formation in
  • diameter

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol
  • trans Golgi network
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Smap2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding
  • GTPase activator activity

Gene-Specific Assays for Results You Can Trust

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